Our story

Rubedo discovers and develops medicines to keep you biologically young by targeting the pathologic cells that drive aging

Rubedo Life Sciences was founded by a group of leading scientists and entrepreneurs with a life-long passion for the science of aging and making therapeutics to help people live a better life longer. They joined forces to merge their knowledge and expertise into a crucible of innovations.

The Rubedo team draws upon more than 150 years of combined experience in multiple fields of research, drug discovery, software engineering and entrepreneurship spanning across aging science, regenerative medicine, medicinal chemistry, artificial intelligence, informatics, drug development.

Our work is transmuting discovery into novel medicines by eliminating cells that enable the aging process and create disease. We aim to extend human health span by restoring biological youth at a cellular level.

Leadership

The Rubedo leadership team is comprises of industry leaders from large pharma, leading biotech companies and pioneers in longevity, early development chemistry, technology, and life sciences. The team has extensive expertise in drug development across early stage to commercialization

Frederick Beddingfield, MD PHD

Chief Executive Officer

Marco Quarta, PhD

Co-Founder
and Chief Scientific Officer

Alex Laslavic

Chief Technology Officer

Julianne Averill, CPA

Chief Financial Officer

Ali Siam, MBA

Chief Business Officer

Mary Spellman, MD

Chief Medical Officer

Ofir Moreno, PhD

SVP Drug Discovery

Board of Directors

Frederick Beddingfield, MD PHD

Chief Executive Officer

Marco Quarta, PhD

Co-Founder
and Chief Scientific Officer

mark gallop, PhD

Co-Founder
and Chairman of the Board

Robert Gould, PhD

Khosla Ventures

Joanna Green, PhD

Ahren Innovation Capital

SCIENTIFIC AND CLINICAL ADVISORY BOARD

Clinical Advisory Board

Mark Lebwohl, MD

Professor & Chairman Emeritus of the Department of Dermatology Icahn School of Medicine at Mount Sinai

Kim Papp, MD, PhD, FRCPC

President, Probity Medical Research Fellow, American Academy of Dermatology

Chris Griffiths, MD, PhD, FRCP

Emeritus Professor of Dermatology University of Manchester Adjunct Professor of Dermatology Kings College of London

Zoe Draelos, MD

Clinical Faculty in the Department of Dermatology at Duke University Founder, Dermatology Consulting Services

Ted Lain, MD, MBA

Executive Director & Principal Investigator Austin Institute for Clinical Research CMO, Sanova Dermatology

Scientific Advisory Board

MARIO LACOUTURE, MD

Chief of Dermatology Division NYU School of Medicine

Cory Hogaboam, PhD

Professor of Medicine, Chronic Lung Disease Cedar-Sinai Hospital

Paul Insel, MD

Emeritus Professor of Medicine and Pharmacology UCSD

Marco Demaria, phd

Professor of Cellular Aging and Senescence, University of Groningen

Francesca Grisoni, Phd

Associate Professor of Molecular Machine Learning Eindhoven University of Technology

JEFF JASPER, PHD

Scientific Advisor, Drug Discovery and Pharmacology

Mark Pegram, MD

Professor of Medical Oncology Stanford University School of Medicine

Lidia Schapira, MD

Professor of Medical Oncology Stanford University School of Medicine

In memoriam

JUDITH CAMPISI, phd

Buck Institute for Research & Aging Professor, Biogerontology

Copyright 2025 by Rubedo Life Sciences, Inc.

MARK gallop, PhD

Co-Founder and Chairman of the Board

Mark Gallop is a veteran drug hunter, chemist and serial entrepreneur. He consults with emerging biotechnology companies in oncology, neuroscience, gastrointestinal disorders and drug design on drug discovery technologies and strategies. He served as Chief Scientific Officer and Director at BlueLight Therapeutics, company that uses a novel structure-function-based approach to develop new therapeutic molecules against challenging drug targets. He is also President at Light Horse Therapeutics, a small molecule drug discovery company employing tools from chemical and computational biology. From 2012 to 2017 he served as the founding Chief Scientific Officer at Nurix, Inc., a venture-backed discovery company formed to explore drug development targeting ubiquitin ligase enzymes, with therapeutic applications spanning across oncology, immunology, inflammation and immuno-oncology. Prior to joining Nurix, he was Senior Vice President of Research and XenoPort, Inc., a company he co-founded in 1999 with the mission of improving the clinical utility of medicines by exploiting active transport mechanisms to optimize their pharmacokinetic properties. While at XenoPort, his team discovered Horizant™, a prodrug of gabapentin that was approved by the FDA in 2011 and the MHW in Japan in 2012 for the treatment of restless legs syndrome. Previously, Dr. Gallop was Senior Director of Combinatorial Chemistry at Affymax. He also served as executive in resident for 5AM Ventures. He is recognized as an early pioneer and international expert in solid-phase combinatorial chemistry. He was a recipient of the ACROS award of the Belgian Organic Synthesis Symposium in 1996 for his outstanding contributions to this field. He is an inventor on more than 100 issued or pending U.S., and PCT patents and an author of over 60 manuscripts in peer-reviewed journals. In 1994, he co-authored a landmark review of the then-emerging field of combinatorial chemistry that has subsequently become one of the most highly cited papers in chemistry. After undergraduate studies in New Zealand, he obtained his Ph.D. degrees in inorganic chemistry from the University of Cambridge and was a Lindemann postdoctoral fellow in the laboratories of Profs. Peter G. Schultz and Robert G. Bergman at the University of California, Berkeley.

Zoe Draelos, MD

Scientific and Clinical Advisory Board Clinical Faculty in the Department of Dermatology at Duke University Founder, Dermatology Consulting Services

Zoe Diana Draelos, a member of Sigma Xi research honorary and Alpha Omega Alpha medical honorary, is author of 14 books including Cosmetics in Dermatology and Hair Cosmetics. She is the editor of Cosmetic Dermatology: Products and Procedures (third edition) and Cosmeceuticals (fourth edition) with translations into 7 languages. She has contributed chapters to 44 textbooks, written 173 posters, served as the principle investigator on 862 studies, written 650 published papers, served on or contributed to 38 journal editorial boards, functioned as the editor-in-chief of the Journal of Cosmetic Dermatology for 10 years, and was a past member of the Board of Directors of the American Academy of Dermatology and the American Society for Dermatologic Surgery. She was elected Vice-President of the American Academy of Dermatology. She is recognized as a pioneer in cosmetic dermatology and received a lifetime achievement award from Health Beauty America for her research and the 2008 DermArts award for her contributions to dermatology. In 2010, she received the Albert Kligman Innovation Award and in 2016 she was awarded a Presidential Citation from the American Academy of Dermatology for her research contributions to advance the specialty. She received the prestigious Maison deNavarre award from the Society of Cosmetic Chemists for her contributions to the art and science of cosmetics in 2017. In 2019, she was the inaugural recipient of the Florence Wall Award from the Society of Cosmetics Chemists. She has been the principal investigator on over 750 studies and the primary investigator for over 300. She has worked with pharmaceutical and cosmetic companies from Aveda to Colgate to Pfizer. She has published 574 papers and delivered numerous presentations, and she is a member of the Sigma Xi research honorary and the Alpha Omega Alpha medical honorary. Zoe earned both a bachelor’s in mechanical engineering (1979) and a medical doctorate from the University of Arizona (1983), before doing her internship in internal medicine and residency in dermatology here as well. As an undergraduate, she was selected as a Rhodes Scholar, an honor that foreshadowed her remarkable career achievements.

Mario E. Lacouture, MD

Chief, Dermatology, NYU Langone Hospital; Professor of Medicine at NYU Grossman School of Medicine; Medical Director of the Symptom Management Program at the Perlmutter Cancer Center on Long Island

Before joining NYU Langone Health, Dr. Lacouture was an Attending Physician and Program Director of Oncodermatology and Research in the Dermatology Service at Memorial Sloan Kettering Cancer Center (MSKCC) in Manhattan. He was also a Professor in the Department of Dermatology at Weill Cornell Medicine in New York. He conducted his postdoctoral work at Brigham and Women’s Hospital in Boston, MA, an internship in General Surgery at Cleveland Clinic and residency in dermatology at The University of Chicago, IL. He received his M.D. degree from Javeriana University in Bogota, Colombia, where he grew up. Dr Lacouture began his career in Oncodermatology at The University of Chicago. During his first faculty appointment at Northwestern University, Dr Lacouture received a Zell Scholarship and a Career Development Award from the Dermatology Foundation, and established the first clinical program focused on dermatologic care in cancer patients and survivors. During this time, he initiated the first clinical trials in Oncodermatology, and described mechanisms and treatments on adverse events to novel cancer therapies, published in the Journal of Clinical Oncology and Nature Reviews Cancer.

Dr Lacouture founded the Skin Toxicity and the Oncodermatology Study Groups of the Multinational Association of Supportive Care in Cancer, is on the Guidelines Advisory Committee of the American Society of Clinical Oncology, and the Editorial Board of Cancer.Net. In 2012, CancerCare named Dr Lacouture as Physician of the Year for his contributions to the education of people living with cancer, and he has been selected as a Top Doctor in America and New York by Castle Connolly and New York Magazine since 2014. Dr Lacouture has published over 280 articles in peer-reviewed journals and is the author of Dr Lacouture’s Skin Care Guide for People Living With Cancer and Editor of the textbook Dermatologic Principles and Practice in Oncology. Dr Lacouture is the PI for numerous clinical trials aimed towards the treatment and understanding of adverse events related to cancer therapies and has received funding from the NIH to better understand these untoward events, with the goal of advancing cancer care through skin health.

Cory Hogaboam, PhD

Cedars-Sinai Professor of Medicine, Chronic Lung Diseases

Dr. Cory M. Hogaboam, PhD is a Professor of Medicine in the Women’s Guild Lung Institute at Cedars Sinai Medical Center. Dr. Hogaboam is also an Adjunct Professor of Pathology at the University of Michigan Medical School. His research group currently employs genomic, proteomic and bioinformatic approaches to analyze mechanisms contributing to fibrotic and immune system-directed responses in idiopathic pulmonary fibrosis (IPF), lung cancer, sarcoid, hypersensitivity pneumonitis, chronic obstructive pulmonary disease (COPD), and asthma utilizing human tissue- and blood-derived cells including fibroblasts, mesenchymal progenitors and various immune cell types that are typically present in abundance in these pulmonary diseases. His group also uses translational approaches through the development of humanized SCID mouse models of IPF, cancer, and asthma. He earned a Bachelor of Science degree in Zoology from the University of Calgary, AB, Canada in 1989. He also holds a Doctorate in Pharmacology (1993) from the same institution. Dr. Hogaboam then engaged in Postdoctoral training in Immunology at McMaster University, Hamilton, ON, Canada from 1993 to 1996. In 1996, Dr. Hogaboam joined the faculty of the Department of Pathology at the University of Michigan Medical School as a Visiting Scholar. He became a faculty member of the Department at the rank of Research Investigator in 1998, Assistant Professor in 2002, Associate Professor in 2004, and full Professor in 2008. Dr. Hogaboam joined the faculty at Cedars Sinai Medical Center in September of 2013. Hogaboam is a member of several professional organizations including the American Association of Immunologists, the American Thoracic Society, and the American Association of Allergy, Asthma and Immunology. He is presently serving on the editorial board of the American Journal of Respiratory and Critical Care Medicine and the Journal of Clinical Investigation Insight. Dr. Hogaboam has authored or co-authored approximately 281 peer-reviewed manuscripts and 31 book chapters. He has authored or co-authored 11 patents on therapeutic interventions for lung and liver. Dr. Hogaboam has received financial research support from the National Institutes of Health, American Lung Association, Canadian Institutes of Health Research, and several Industry sponsors.