Physical:
Lifting up to 20 lbs occasionally, standing, bending, repetitive movement, etc.
WE ARE HIRING!
WE WELCOME ALL APPLICANTS
regardless of gender, sexual orientation, ethnicity, race, education, age,
or other personal characteristics
Rubedo Life Sciences is a biotechnology company with active research programs related to
age-related diseases with a focus on inflammation and fibrosis. We are seeking a motivated
and dynamic Scientist / Senior Scientist to help build the capabilities needed for translational
research and preclinical development, advancing the discovery of molecular targets and
therapeutics for age-related pathobiologies. The successful candidate will be an experienced
drug-discovery scientist.
Responsibilities include:
- Work closely with our Bioinformatics specialists to identify novel age-related disease targets and signaling pathways
- Design, conduct and manage experiments related to the discovery of therapeutic drug mechanisms targeting cellular senescence and age-related diseases
- Analysis of data, and preparation of associated documentation and reports
- Presentation of experimental results at meetings
- Develop protocols and maintain detailed documentation of procedures
- Train and supervise research associates
Minimum Requirements:
- Ph.D. or equivalent experience in Biology, Biochemistry, Molecular Biology, Immunology,Physiology, Pharmacology or related discipline
- Three or more years of relevant industry experience in target discovery and validation
- Established knowledge base in at least one aspect of age-related disease biology
- Experience in the study of chronic diseases in one or more of the following disease areas: metabolic, inflammatory, fibrotic or other age-related diseases (such as Metabolic, Inflammatory and Fibrotic Diseases)
- Deep understanding of molecular pathways driving pathological tissue degeneration
- Proven ability to solve complex problems by undertaking innovative approaches and applying state-of-the art technologies
Preferred Experience And Skills:
- Strong understanding of tissue homeostasis and immunology
- Experience with single cell isolation (such as fluorescent activated cell sorting)
- Experience in whole animal physiology and in vivo models of fibrosis and/or inflammatory diseases
- Actively seeks and embraces feedback with the goal of continuous performance improvement
- Experience with computational and statistical approaches for high-dimensional data analysis, such as single cell RNA sequencing and/or proteomics
- Experience with target validation in drug discovery
- Excellent communication skills and ability to work in multidisciplinary project teams
Environmental Conditions / Physical Demands::
Enviromental:
Exposure to wet lab environment, blood borne pathogens, and toxic or caustic chemical or reagents
Work location:
Sunnyvale, CA, USA
Rubedo Life Sciences is a biotechnology company with active research programs related to age-related diseases with a focus on inflammation and fibrosis. We are seeking a motivated and dynamic Senior Scientist to help build the capabilities needed for translational research and development, advancing the discovery of molecular targets and therapeutics for age-related pathobiologies, including fibrosis. The successful candidate will be an experienced drug-discovery scientist acting as the in vivo lead on various programs. This involves directing our team of in vivo scientists and collaborating with a cross-functional team of experts and working with CRO’s to facilitate successful advancement of programs.
Responsibilities include:
- Employ drug discovery principles while guiding programs through pharmacokinetic studies, lead-optimization, animal model development and proof of concept in validated efficacy models
- Interpret data and assist in understanding PK/PD relationships
- Design, conduct and manage experiments related to the discovery of therapeutic drug mechanisms targeting cellular senescence and age-related diseases
- Analysis of data, and preparation of associated documentation and reports
- Presentation of experimental results at internal meetings and scientific conferences
- Develop protocols and maintain detailed documentation of procedures
- Train and supervise scientists and research associates
Minimum Requirements:
- Ph.D. or equivalent in Biology, Physiology, Pharmacology, Biochemistry, Immunology, or related discipline
- Five or more years of relevant industry experience
- Experience in the study of chronic diseases in one or more of the following disease areas: metabolic, inflammatory, fibrotic or other age-related diseases
- Proven ability to solve complex problems by undertaking innovative approaches and applying state-of-the art technologies
- Demonstrated experience in moving programs across stage-gates
Preferred Experience And Skills:
- Established knowledge base in at least one aspect of age-related disease biology
- Experience selecting and managing CROs
- Demonstrated experience in project leadership
- Excellent communication skills and ability to work in multidisciplinary project teams
- Actively seeks and embraces feedback with the goal of continuous performance improvement
Environmental Conditions / Physical Demands::
Physical:
Lifting up to 20 lbs occasionally, standing, bending, repetitive movement, etc.
Enviromental:
Exposure to wet lab environment, blood borne pathogens, and toxic or caustic chemical or reagents
Work location:
Sunnyvale, CA, USA
Silicon Valley, CA, USA
Copyright 2020 by Rubedo Life Sciences, inc