WE ARE HIRING!

WE WELCOME ALL APPLICANTS

regardless of gender, sexual orientation, ethnicity, race, education, age,
or other personal characteristics

Rubedo Life Sciences is a biotechnology company with active research programs related to
age-related diseases with a focus on inflammation and fibrosis. We are seeking a motivated
and dynamic Scientist / Senior Scientist to help build the capabilities needed for translational
research and preclinical development, advancing the discovery of molecular targets and
therapeutics for age-related pathobiologies. The successful candidate will be an experienced
drug-discovery scientist.

Responsibilities include:

  • Work closely with our Bioinformatics specialists to identify novel age-related disease targets and signaling pathways
  • Design, conduct and manage experiments related to the discovery of therapeutic drug mechanisms targeting cellular senescence and age-related diseases
  • Analysis of data, and preparation of associated documentation and reports
  • Presentation of experimental results at meetings
  • Develop protocols and maintain detailed documentation of procedures
  • Train and supervise research associates

Minimum Requirements:

  • Ph.D. or equivalent experience in Biology, Biochemistry, Molecular Biology, Immunology,Physiology, Pharmacology or related discipline
  • Three or more years of relevant industry experience in target discovery and validation
  • Established knowledge base in at least one aspect of age-related disease biology
  • Experience in the study of chronic diseases in one or more of the following disease areas: metabolic, inflammatory, fibrotic or other age-related diseases (such as Metabolic, Inflammatory and Fibrotic Diseases)
  • Deep understanding of molecular pathways driving pathological tissue degeneration
  • Proven ability to solve complex problems by undertaking innovative approaches and applying state-of-the art technologies

Preferred Experience And Skills:

  • Strong understanding of tissue homeostasis and immunology
  • Experience with single cell isolation (such as fluorescent activated cell sorting)
  • Experience in whole animal physiology and in vivo models of fibrosis and/or inflammatory diseases
  • Actively seeks and embraces feedback with the goal of continuous performance improvement
  • Experience with computational and statistical approaches for high-dimensional data analysis, such as single cell RNA sequencing and/or proteomics
  • Experience with target validation in drug discovery
  • Excellent communication skills and ability to work in multidisciplinary project teams

Environmental Conditions / Physical Demands::

Physical:

Lifting up to 20 lbs occasionally, standing, bending, repetitive movement, etc.

Enviromental:

Exposure to wet lab environment, blood borne pathogens, and toxic or caustic chemical or reagents

Work location:

Sunnyvale, CA, USA

Rubedo Life Sciences is a biotechnology company with active research programs related to age-related diseases with a focus on inflammation and fibrosis.  We are seeking a motivated and dynamic Senior Scientist to help build the capabilities needed for translational research and development, advancing the discovery of molecular targets and therapeutics for age-related pathobiologies, including fibrosis. The successful candidate will be an experienced drug-discovery scientist acting as the in vivo lead on various programs. This involves directing our team of in vivo scientists and collaborating with a cross-functional team of experts and working with CRO’s to facilitate successful advancement of programs. 

Responsibilities include:

  • Employ drug discovery principles while guiding programs through pharmacokinetic studies, lead-optimization, animal model development and proof of concept in validated efficacy models
  • Interpret data and assist in understanding PK/PD relationships
  • Design, conduct and manage experiments related to the discovery of therapeutic drug mechanisms targeting cellular senescence and age-related diseases
  • Analysis of data, and preparation of associated documentation and reports
  • Presentation of experimental results at internal meetings and scientific conferences
  • Develop protocols and maintain detailed documentation of procedures
  • Train and supervise scientists and research associates

Minimum Requirements:

  • Ph.D. or equivalent in Biology, Physiology, Pharmacology, Biochemistry, Immunology, or related discipline
  • Five or more years of relevant industry experience
  • Experience in the study of chronic diseases in one or more of the following disease areas: metabolic, inflammatory, fibrotic or other age-related diseases
  • Proven ability to solve complex problems by undertaking innovative approaches and applying state-of-the art technologies
  • Demonstrated experience in moving programs across stage-gates

Preferred Experience And Skills:

  • Established knowledge base in at least one aspect of age-related disease biology
  • Experience selecting and managing CROs
  • Demonstrated experience in project leadership
  • Excellent communication skills and ability to work in multidisciplinary project teams
  • Actively seeks and embraces feedback with the goal of continuous performance improvement

Environmental Conditions / Physical Demands::

Physical:

Lifting up to 20 lbs occasionally, standing, bending, repetitive movement, etc.

Enviromental:

Exposure to wet lab environment, blood borne pathogens, and toxic or caustic chemical or reagents

Work location:

Sunnyvale, CA, USA

Silicon Valley, CA, USA

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